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Symbol Name ID |
Bcl2
B cell leukemia/lymphoma 2 MGI:88138 |
| ! | Indicates phenotype varies with strain background. |
| Darker colors indicate more annotations |
| Human Phenotypes | Renal cell carcinoma |
| Disease(s) Associated with BCL2 | |
| renal cell carcinoma |
| Mouse Phenotypes | abnormal glomerular capillary endothelium morphology |
abnormal kidney vasculature morphology |
increased metanephric mesenchyme apoptosis |
increased kidney apoptosis |
increased renal glomerulus apoptosis |
increased kidney cell proliferation |
kidney cyst |
kidney cortex cyst |
kidney medulla cyst |
polycystic kidney |
enlarged kidney |
abnormal kidney morphology |
abnormal kidney cortex morphology |
abnormal glomerular capsule parietal layer morphology |
parietal capsular epithelium metaplasia |
decreased glomerular capsule space |
abnormal podocyte morphology |
podocyte foot process effacement |
podocyte hypertrophy |
abnormal renal glomerulus morphology |
expanded mesangial matrix |
mesangiolysis |
glomerulosclerosis |
decreased renal glomerulus number |
renal glomerular synechia |
renal glomerulus hypertrophy |
abnormal kidney corticomedullary boundary morphology |
abnormal kidney development |
abnormal kidney mesenchyme morphology |
abnormal metanephric mesenchyme morphology |
abnormal metanephric ureteric bud development |
small metanephros |
abnormal nephrogenic zone morphology |
delayed kidney development |
abnormal renal tubule epithelium morphology |
abnormal kidney interstitium morphology |
abnormal kidney medulla morphology |
decreased kidney weight |
increased compensatory renal growth |
small kidney |
renal hypoplasia |
decreased nephron number |
dilated distal convoluted tubule |
dilated proximal convoluted tubule |
dilated renal tubule |
renal tubule hypertrophy |
kidney degeneration |
pale kidney |
impaired branching involved in ureteric bud morphogenesis |
abnormal ureteric bud elongation |
small ureteric bud |
kidney failure |
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| Availability | Mouse Genotype | ||||||||||||||||||||||||||||||||||||||||||||||||||||
| Bcl2tm1Dlo/Bcl2tm1Dlo | ! | ||||||||||||||||||||||||||||||||||||||||||||||||||||
| Bcl2tm1Mpin/Bcl2tm1Mpin | |||||||||||||||||||||||||||||||||||||||||||||||||||||
| Bcl2tm1Sjk/Bcl2tm1Sjk | |||||||||||||||||||||||||||||||||||||||||||||||||||||
| Bcl2tm1Tsu/Bcl2tm1Tsu | |||||||||||||||||||||||||||||||||||||||||||||||||||||
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/23/2024 MGI 6.23 |
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